Antaraal - Online Marathi Magazine: Content / Nov2005_lekh Embryonic StemCells By Yashvant Karkhanis

Aimb;>y;;|in;k: s!em; s;eDs;

EMBRYONIC STEM CELLS ; A NEW PROMISE FOR A HEALTHY LIFE
ES Cells

2005 s;;lcy;; aQy;Z;Iy; in;v;#[;Uk:It; m;;|#re!r b;;|b; x;If:r y;;n;I p;>eis;#e]! b;ux; a;i[; s;en;e!r j;;|n; k:erI y;;]n;; aek: p;>Sn; iv;c;;rl;.
j;r t;umhI in;v;#Un; a;l;t; t;r t;umhI ae]ib;>y;;|in;k: s!em; s;el irs;c;* s;ur: @ev;;l k:; ?
p;>eis;#e]! b;ux; Wdg;;rle, n;;hI. k:;r[; m;l; k:;hI j;Iv; j;g;v;[y;;s;;@I wt;r j;Iv; m;;r;y;c;e n;;hIt;. m;I a;Q;Ic; 60 s!em; se;l l;wns;n;; Wp;y;;eg; k:r;y;c;I p;rv;;n;g;I idlelI a;he. ty;;Wp;r m;I j;;[;;r n;;hI.
s;en;e!r k:erI mh[;;le m;I j;r in;v;#Un; a;l;e t;r Hy;; ES cells v;rc;I s;v;* b;]Q;n;] k:;$Un; !;k:en;. a;p;Dy;; s;g;Ly;;]c;e j;v;Lc;e B;;w*b;]d , n;;t;ev;;wk: p;;ik:*ns;n;, #;y;b;ei!s;, a\lz;;y;m;r, k:|ns;r a;id r;eg;;]n;I p;I#It; a;het;. ES cells m;uLe Hy;;t;le K;Up; r:g[; b;re h;eW: x;k:t;Il, j;;st; j;g;U x;k:t;Il. ES cell s;]x;;eQ;n; ty;;]n;; n;v;I a;x;; deW: x;k:[;;r a;he. IVF ikln;Iks; m;Q;e v;;p;r:n; Wrlele ik:t;It;rI g;B;* k:;r[;;ix;v;;y; g;;e@v;leDy;; isq;t;It; @ev;le j;;t;;t; ik:v;; K;Up;x;; dex;;]t; g;;e@v;[y;;c;I t;]F;e p;urex;I iv;k:is;t; n; z;;Dy;;m;uLe as;e g;B;* f:ek:le j;;t;;t;. m;I he b;Ij;;[;U ty;;]cy;; p;;lk:;]cy;; p;rv;;n;g;In;e p;rt; v;;p;rIn;. ES Cells Hy;; p;ex;I p;>y;;eg;x;;Let; p;e!MI i#x;m;Qe; v;;$v;leDy;; as;t;;t;. ty;; a;w*cy;; g;B;;*x;y;;t;Un; a;leDy;; n;s;t;;t;. ty;;m;uLe j;Iv;;l; m;;r;y;c;; p;>Sn;c; y;et; n;;hI. a;i[; m;uKy; g;;e{! mh[;j;e b;;k:Icy;; dex;;]p;eZ;; am;eirk:; Hy;; s;]x;;eQ;n;;t; m;;g;e p;#lelI m;l; a;v;#[;;r n;;hI.
dus;Ry;; idv;x;I a\lz;;y;m;r r;eg;;n;e p;I#leDy;; m;;j;I aQy;Z; r;|n;;D# reg;n;cy;; p;tn;I n;|ns;I reg;n; y;;]n;Ie p;>eis;#e]! b;ux;n;; ES cells v;r s;]x;;eQ;n; s;ur: @ev;;y;c;I iv;n;]t;I k:elI. ty;; mh[;;Dy;;, he s;]x;;eQ;n; j;r a;Q;I s;ur: z;;l] as;t;] t;r m;;z;e p;it; v;;c;le as;t;e. aek:; ap;G;;t;;n;e b;rIc; v;{;* K;uc;I*l; iK;LUn; as;leDy;; iK;>s!;ef:r rIvHj;n;ehI he s;]x;;eQ;n; j;;er;t; s;ur: @ev;;y;c;I k:Lk:LIc;I iv;n;]t;I k:elI. m;l; WB;] r;h[y;;s;;@I Q;#Q;;k:! p;;y; p;;ihj;e a;het;. g;;v;;t; %;n;p;Ek:I c;;lt; j;;W:n; im;F;;b;r;eb;r g;pp;; m;;r;y;l; v; ty;;n;]t;r G;rI y;eW:n; p;;y; t;;[;Un; deW:n; aeK;;d; is;n;em;; !IvhIv;r b;G;[;e he m;;z;] sv;pn; a;he. ty;;s;;@I ES cells s;]x;;eQ;n; hI aek:c; a;x;; m;l; WrlelI a;he.
m;;y;k:l g;>In; n;;v;;c;; aek: n;! p;;ik:*ns;n;n;e b;rIc; v;{;*] a;j;;rI a;he. ty;;n;e y;uin;vhis;*!I a;|f: iv;sk:;|ins;n;l; 3 k:;e!I #;|ls;*c;I m;dt; ES cell v;r s;]x;;eQ;n; k:r[y;;s;;@I idlelI a;he.
ES cells v;Eêk:Iy; x;;sF;;c;; p;;y;;c; b;dlUn; !;k:[;;r a;he. Hy;; p;ex;I x;rIr;cy;; jy;; B;;g;;l; j;x;I j;r:r a;he ty;;n;us;;r b;dlt;; y;et;;t;. ty;; m;UF;ip;]#;cy;; p;ex;I]s;;rKy;; h;et;;t;. aeK;;ê; h&dy;;cy;; p;ex;I aQ;U as;leDy;; r:g[;;t; ty;; in;r;eg;I h&dy;;cy;; p;ex;I b;n;U x;k:t;;t;, #;y;b;ei!k: p;ex;]!m;Qy;e ty;; sv;t;/hUn; wns;uiln; b;n;v;U x;k:[;;Ry;; sv;;duip;]#;s;;rKy;; k:rt;; y;et;Il (pancreas ) , p;;ik:*ns;n; z;;leDy;; r;egy;;]cy;; m;]edUt;Un; g;;y;b; z;;lele #;ep;;im;n; n;;v;;c;; sF;;v; Hy;; p;ex;I in;m;;*[; k:r: x;k:t;Il, rT;:;c;; k:|ns;r as;leDy;; r;egy;;l; Hy;; p;ex;Im;uLe n;v;In; rT;: b;n;v;t;; y;ewl. ES cells m;Q;Un; ag;dI h;#;cy;; p;ex;I deK;Il n;vy;;n;e b;n;v;t;; y;et;Il.
ES cells n;I j;g;;c;e lZ; v;eQ;Un; G;et;le a;he. as;;Qy; r;eg;;]cy;; r:g[;;]n;; j;g;[y;;c;I n;v;In; a;x;; de[;;Ry;; Hy;; p;ex;Im;uLe Regenerative medicine ax;I n;v;I x;;K;; in;m;;*[; h;eW: x;k:el. p;;iSc;m;;ty; v; p;;Ev;;ty; s;]x;;eQ;k:;]n;; Hy;; p;ex;Idv;;r;, n;v;n;v;In; x;;eQ; l;v;;y;c;;, j;[;U s;uv;[;*y;;eg;c; c;;lUn; a;lel; a;he.
ES cells mh[;j;e k:;y; ? ty;; k:x;; as;t;;t; ? Hy;; p;ex;I]m;Q;e ag;i[;t; k:;L;p;y;*t; iv;B;;j;n; h;eW:n; iv;x;e{; p;ex;I in;m;;*[; k:r;y;c;I Z;m;t;; as;t;e. j;evh; x;uF;:j;]t;Uc;e (sperm) sF;Ib;Ij;;b;r;eb;r (ovum) m;Iln; h;et;e, t;evh; g;B;;*c;I v;;$ s;ur: h;et;e.Hy;; m;Iln;;m;uLe j;I p;ex;I t;y;;r h;et;e, it;cy;;t; s;]p;U[;* m;;n;v; b;n;v;;y;c;I Z;m;t;; as;t;e, mh[;Un; it;l; s;]p;U[;* s;Z;m; p;ex;I mh[;t;;t; (Totipotent; their potential is total). hI p;ex;I s;]m;Iln; z;;Dy;;cy;; k:;hI t;;s;;]cy;; a;t; a;p;Dy;;s;;rKy;;c; s;]p;U[;* s;Z;m; p;ex;I t;y;;r k:rt;e. Hy;;t;Il aek:n;aek: p;ex;I sF;Icy;; g;B;;*x;y;;t; re;p;[; k:eDy;;v;r @ev;Dy;;v;r aK;]# m;;n;v; k:r: x;k:t;e. ax;; j;evh; de;n; p;ex;I iv;B;;g;Dy;; j;;t;;t; t;evh; n;;hI k:; j;uLI m;ul] j;nm;t; ? m;Iln;;n;]t;r c;;r idv;s;;]n;I v; an;ek: v;eL; iv;B;;j;n; z;;Dy;;n;]t;r , Hy;; s;]p;U[;* s;Z;m; p;ex;Im;Q;Un; iv;ix;{! p;ex;I]c;I in;m;I*t;I vh;y;l; s;ur:v;;t; h;et;e.
Blastocyst

p;>q;m; aek: g;;el;k:;r t;y;;r h;et;;e. ty;;l; bl;s!;eis;s!(Blastocyst) mh[;t;;t;. Hy;;cy;; b;;her aek: p;ex;I]c;; q;r v; a;t;Dy;; b;;j;Ul; aek: p;ex;I]c;; s;m;Uh as;t;;e, jy;;l; wn;r se;l m;;s; (Inner cell mass) mh[;t;;t;. b;;hercy;; q;r;p;;s;Un; pl;se;]!;c;I ( v;;r ) in;im;*t;I h;et;e v; wn;r se;l m;;s;p;;s;Un; m;;n;v;I x;rIr;c;I. wn;r se;l m;;s;cy;; p;ex;I s;]p;U[;* m;;n;v;;c;I in;im;*t;I k:r: x;k:t; n;;hIt; k:;r[; ty;; pl;s;e]!; b;n;v;U x;k:t; n;;hIt;, mh[;Un; wn;r se;l m;;s;cy;; p;ex;I]n;; plUrIp;;e!]! (pluripotent) as;e mh[;t;;t;. mh[;j;e K;Up; t;Rhecy;; p;ex;I. p;r]t;u ty;; s;]p;U[;* s;Z;m; n;s;t;;t; mh[;j;e v;eg;Ly;; x;bd;t; s;;]g;;y;c; z;;l] t;r ty;;]cy;;t; sF;Icy;; g;B;;*x;y;;t; @ev;Dy;;v;r m;;n;v; im;n;;*[; k:r;y;c;I Z;m;t;; n;s;Dy;;m;uLe y;; Totipotent h;eW: x;k:t; n;;hIt;. wn;r se;l m;;s; mh[;j;ec; s!em; s;eDs; p;ex;Ic;; j;n;k:.
Stem cell x;;sF; j;v;Lj;v;L 30 v;{;* j;un;] a;he. 1971 s;;lI Hy;; p;ex;I p;>q;m; W]dr;t; x;;eQ;[y;;t; a;Dy;; v; ty;; vd;re k:r[y;;t; a;lelI j;uj;b;I Wp;;y;y;;ej;n;; K;Up; v;{;*} aist;tv;;t; a;he. Wd;hr[;;q;* j;evh; k:|ns;r p;ex;]!n;; b;;en;m;|r;e !M;ns;pl;]! idl j;;t;], t;evh; ik:m;;eq;erp;In;e n;;x; p;;v;lel; B;;g; p;un;*j;Iv;It; k:r;y;l; s!em; se;Ds; idDy;; j;;t;;t;. t;rIhI ag;dI hDlIhDlIp;y;*t; x;;sF;N;]n;; s!em; s;eDs;m;uLe ik:t;I t;Rhec;; f:;y;d; h;eW: x;k:t;;e Hy;; g;;e{!Ic;; a]d;j; a;l; n;vht;;.s!em;s;eDs; aDp;j;Iv;I as;Dy;;m;uLe v; l|b;m;Q;e v;;$v;[;] k:@I[; as;Dy;;m;uLe s!em;se;Ds;cy;; s;]x;;eQ;n;;t; a;#k:;@I in;m;;*[; z;;lI h;et;I. p;[; 1998 s;;lI iv;sk:;|ins;n; y;uin;vhis;*!Ic;e #;|. q;;|m;s;n; v; j;;|ns; h;|p;ik:ns; y;uin;vhis;*!Im;Q;Il #;|.ig;y;rh;!* y;;]n;I sv;t;]F;p;[;e Hy;; p;ex;I l|b;m;Q;e k:x;; v;;$v;t;; y;et;Il Hy;;c;; x;;eQ; l;v;l;. #;| q;;|m;s;n;n;I bl;s!;eis;s! s!ej;m;Q;e as;leDy;; g;B;;*m;Q;Dy;; wn;r se;l m;;s;p;;s;Un; plu;irp;;e!]! p;ex;I v;eg;Ly;; k:eDy;;. ty;;]n;I IVF ikln;Ik:m;Q;Dy;; p;ex;]!cy;; s;]m;t;In;e g;B;* im;Lv;le. plUirp;;e!]! p;ex;I g;B;;*t;Dy;; wn;rse;lm;;s; p;;s;Un; v;eg;Ly;; k:eDy;; v; ty;; p;e!MI i#x;m;Q;e v;;$v;Dy;;.ax;; rIt;In;e ty;;]n;I pluirp;;e!]! se;l l;wn; c;;lU k:elI. Hy;; Wl! #;|.ig;arh;!*n;I g;B;*p;;t; k:eleDy;; g;B;;*p;;s;Un; pluirp;;e!]! p;ex;I im;Lv;Dy;;. j;rI Hy;; d;en; s!em;s;el p;ex;Ic;; Wg;m; v;eg;L; as;l; t;rI, ty;;]c;I r:p;re{;; j;v;Lj;v;L s;;rK;Ic; h;et;I. Hy;; d;en; x;;sF;N;]n;I l;v;lel; h; x;;eQ; ES cells s;]x;;eQ;n;;c;; m;htv;;c;; !pp;; m;;n;l; j;;t;;e.
Stem Cells

ES cells m;uLe m;;n;v;;s;;@I ag;i[;t; f:;y;de h;eW: x;k:t;;t;.
1. m;;n;v;;c;I in;im;*t;I k:x;I h;et;e he s;m;j;[;e ait;x;y; ikl{! a;he. ES cells cy;; s;]x;;eQ;n;;m;uLe he k:L[y;;s; s;;ep;e j;;w*l. ES cells cy;; p;&{@ B;;g;;v;r as;leDy;; k:;hI iv;ix;{! j;;g;;]k:rv;I m;;n;v;;cy;; in;im;*t;Ic;e a;dex; j;n;uk:;]n;; (Genes) k:s;e im;Lt;;t;, he s;]x;;eQ;n; j;r ES cells m;ub;lk: p;>m;;[;;t; Wp;lbQ; z;;Dy;; t;r f:;rc; s;;ep;] j;;w*l. he a;dex; vy;v;isq;t; a;le t;r m;;[;Us; in;re;g;I j;nm;t;;e p;[; c;uk:Ic;e s;]dex; idDy;;m;uLe j;nm;j;;t; vy;]g; WdB;v;U x;k:t;e v;; n;]t;r k:\ns;rs;;rK;e as;;Qy; r;eg; WdB;v;t;;t;.p;ex;Ic;e k:;y;* s;urLIt; k:s;e c;;lt;e he j;r n;I! k:Lle t;r G;;t;k: a;j;;r k:x;;m;uLee h;et;;t; v; ty;;]n;; k:;e[;c;I a;E{;Q;e l;g;U p;#t;Il hehI s;]x;;eQ;k:;n;; x;;eQ;t;; y;ew*l.
2. m;;n;v;I pluirp;;e!]! p;ex;I s;]x;;eQ;n;;m;uLe a;E{;Q;;c;I in;imI*t;I v; ty;;c;I s;uriZ;t;t;; p;;rK;t;; y;ewl. s;Qy;; n;vy;; a;E{;Q;;c;I in;im;*t;I hI f:;r dIG;* v; K;ic;*k: b;;b; a;he. k:Q;Ik:Q;I k:;e!y;;v;Q;I #;\ls;* v; v;{;;*n;uv;{;;*c;e s;]x;;eQ;n; K;c;* k:r:n;hI t;I a;E{;Q;e m;;n;v;I Wp;y;;eg;;s;;@I ay;;egy; as;lelI a;$LUn; y;et;;t;. Hy;;m;uLe p;Ex;;c;; v; v;eLec;; ap;vy;y; h;et;;e. ES cells j;r; s;hj; rIty;; Wp;lbQ; z;;Dy;; t;r #Mg; k]:p;ny;; n;v;In; a;E{;Q;;c;e p;>y;;eg; ty;; p;ex;Iv;r k:rt;Il v; j;I a;E{;Q;e ES cells v;r s;]x;;eQ;n; k:r:n; Wp;y;uT;: v; iht;;v;h a;$Lt;Il, ty;; a;E{;Q;;c;ec; n;]t;r l\b;m;Q;Dy;; p;>;[]y;;v;r p;>y;;eg; h;eW: x;k:t;Il.
3. pluirp;;e!]! p;ex;Ic;; h;e[;;r; s;v;;*t; dUrg;;m;I f:;y;d; mh[;j;e s;el q;erp;I. m;;n;v;;l; h;e[;;re b;rec;s;e a;j;;r p;ex;I]c;e x;rIr;t;le k:;y;* q;;]b;Dy;;m;uLe v;; ib;G;#Dy;;m;uLe h;et;;t;.s;Qy;; ib;G;;# z;;leDy;; av;y;v;;cy;; j;;g;I d;n; k:elele av;y;v; (Donor organs) b;s;v;le j;;t;;t;.dudEv;;n;e jy;;cy;; av;y;v;;t; ib;G;;# z;;l; a;he ax;; r:g[;;]c;I s;]Ky;; j;e l;ek: av;y;v; d;n; k:r: wic%t;;t; ax;; le;k:;p;eZ;; ik:t;It;rI p;!In;e aiQ;k: as;t;e.ty;;m;uLe av;y;v; im;L[y;;s; iv;l]b; h;et;;e.t;s;ec; d;n; k:ellee av;y;v; x;rIr;t; b;s;v;[;] he deK;Il K;Up; K;c;;*c;e k:;m; a;he.pluirp;;e!]! p;ex;I k:#Un; he ib;G;;# z;;leDy;; av;y;v;;s;;rKy;; p;ex;I t;y;;r k:r:n; G;et;Dy;; t;r m;Q;um;eh, s;]iQ;v;;t;, alz;;y;m;r, h&dr;eg;,m;jj;;s;]sq;ec;e r;eg; ax;; as;]Ky; re;g;;c;e s;m;UL in;r;k:r[; k:r[y;;t; y;eW: x;k:el. v;Eêik:y; x;;sF;;t;Il k:u@lIhI x;ky;t;; Hy;; p;ex;Im;uLe v;]ic;t; r;hU x;k:[;;r n;;hI. j;uny;; h&dre;g;;cy;; duK;[;ek:Ry;;l; n;v;In; p;ex;I G;;t;Dy;;m;uLe ty;;c;] h&dy; n;vy;;n;e k:;m; k:r: x;k:el.pluirp;;e!]! p;ex;Ip;;s;Un; b;n;v;leDy;; h&dy;;cy;; p;ex;I a;j;;rI h&dy;;t; G;;lUn; ty;;c; k:;y;* p;Uv;*v;>t; k:r;y;c;I x;ky;t;; a;he.W]dr;s;;rKy;; wt;r p;>;[y;;]v;r k:elele p;>y;;eg; Hy;; g;;e{!Ic;I is;àt;; det;;t;.
4. m;Q;um;eh;cy;; r:g[;;t; ( #;y;b;ei!s; p;>k:;r 1 ) sv;;duip;]#;cy;; iv;ix;{! “a;y;le! s;eDs; p;ex;Ip;;s;Un; wns;uiln; he dm;;[;t; t;y;;r h;et; n;;hI.Hy;; iv;ix;{! p;ex;I j;r x;rIr;t; G;;t;Dy;; g;eDy;; t;r wns;uiln;c;I w]j;ekx;ns; Gy;;y;l; l;g;[;;r n;;hIt;. pluirp;;e!]! p;ex;In;; j;r a;y;le! p;ex;I s;;rK;] b;dll] t;r #;y;b;ei!s; cy;; s;]x;;eQ;n;;t; K;Up; h;t;B;;r l;g;[;;r a;he. sp;|in;x; s;]x;;eQ;k:];n;I W]dr];m;Q;e Hy;; wns;uiln; in;m;;*[; k:r[;;Ry;; p;ex;I]c;I in;im;*t;I k:elelI a;he.
5. am;erik:et;Il k:;hI s;]x;;eQ;k:;]n;I m;e]dUt;Un; #ep;;im;n; Hy;; d>vy;;c;I in;im;*t;I k:r[;;Ry;; K;;s; p;ex;I]c;I v;;$ k:r[y;;;t; y;x; im;Lv;l] a;he. Hy;; p;ex;I]t; ib;G;;# z;;Dy;;m;uLec; p;;ik*:ns;n; h; r;eg; h;et;;e. #;.ig;y;rh;!*Ucy;; j;;|n; h;;|p;ik:ns;m;Q:Il s;hk:;Ry;;]n;I ES p;ex;I]dv;;r;, aQ;;*]g; z;;leDy;; W]dr;l; p;rt; h;lc;;l k:r[y;;s; WêuT;: k:el] a;he,
6. hEd>;b;d y;eq;Il #;.| p;>s;;d he n;eF; iv;B;;g;t;Il s;]x;;eQ;k: ES p;ex;Ic;; Wp;y;;eg; a]Q;;]c;I à{!I im;Lv;[y;;s;;@I k:rt; a;het;. B;;rt;;m;Q;e h&dr;eg;;c;e p;>m;;[; f:;rc; as;Dy;;m;uLe s;]x;;eQ;k:;c;; dus;r; g;! jy;; ES p;ex;Iv;rIl k:;els!er;|lc;e p;>m;;[; b;r;eb;r a;he, ax;; p;ex;Idv;;r; h&dr;eg;;v;r s;]x;;eQ;n; k:rt; a;he. hUdre;g;;cy;; K;Up; r:g[;;m;Q;e k:;els!er;\lcey;I j;n;uk:;t; (genes) ib;G;;# as;t;;e. Hy;; r:g[;;c;e y;k:&t; (Liver) j;r:rIp;eZ;; j;;st; p;>m;;[;;t; LDL he v;;w*! p;àt;Ic;e k:;eles!er;\l b;n;v;t; as;t;. ax;; in;k:;m;I y;k:&t;;t; jy;;c;] k:;els!er;|lc;] j;n;uk: vy;v;isq;t; a;het; ax;; ES p;ex;I G;;lUn; k:;els!er;|lc;I in;im;*t;I s;uQ;r;v;y;c;; p;>y;tn; k:;hI s;]x;;eQ;k: k:rt; a;het;.
7. 2006 s;;lcy;; s;ur:v;;t;Il; Geron hI k:|ilf:;ein;*y;;t; as;lelI b;;y;;e!ekn;;|l;\ij;k:l k:]p;n;I m;jj;;t;]t;Uc;e r;eg; ES p;ex;Ivd;r; b;re k:r;y;cy;; s;]x;;eQ;n;;l; s;ur:v;;t; k:r[;;r a;he.

Hy;; s;g;Ly;; s;]x;;eQ;n;;l; m;uKy; a#c;[; y;et; a;he t;I mh[;j;e irj;ekx;n;c;I. aek:; m;;[;s;;cy;; p;ex;I dus;Ry;;cy;; x;rIr;t; r;ep;[; k:r;y;l; l;g;Dy;;v;r ty;; lg;ec; b;;her f:ek:Dy;; j;;t;;t;. k:;r[; ty;; d;en; m;;[;s;;]c;I j;n;uk]: s;;rK;I n;s;t;;t;. h; F;;s; dUr k:r;y;l; s;]x;;eQ;k:;]n;I aek: v;eg;LI y;uT;:I y;;ej;lI. it;c; n;;v; a;he Somatic cell nuclear transfer. ( SCNT ) . s;]x;;eQ;k:;]n;I aek:; p;>;[y;;cy;; a]#y;;t;l; ny;uikly;s; k:;$Un; !;k:l;. j;;e B;;g; Wrt;;e ty;;t; g;B;;*cy;; v;;$Is;;@I l;g;[;;rI B;rp;Ur d>vy;e as;t;;t;. ty;;n;]t;r aek:; p;>y;;eg;x;;Let; k:;Lj;Ip;Uv;*k: vy;v;sq;; k:r:n; x;rIr;c;I aeK;;dI p;ex;I ny;Uikly;s; k:;$leDy;; a]#Y;x;ej;;rI @ev;lI j;;t;e v; ty;; de;nhI p;ex;I iv;êut; v; r;s;;y;in;k: p;>iF;:y;; k:r:n; j;;e#Dy;; j;;t;;t;. Hy;; j;;e#Dy;; g;eleDy;; p;ex;It; s;]p;U[;* m;;n;v; in;m;;*[; k:r;y;c;I Z;m;t;; as;t;e. jy;; m;;[;s;;t; hI p;ex;I G;;t;lI j;;w*l t;;e t;I b;;her f:ek:[;;r n;;hI k:;r[; t;I p;ex;I ty;;c;Ic; a;he. ax;; t;Rhen;e SCNT v;;p;r:n; Hy;; p;ex;Ip;;s;Un; bl;s!;eis;s! t;y;;r h;ew*l. ty;;t;Il wn;r se;l m;;s; p;;s;Un; pluirp;;e!]! p;ex;I in;m;;*[; h;eW: x;k:t;Il. s;g;LI Genetic m;;iht;I ny;Uikly;s;m;Q;ec; as;Dy;;m;uLe Hy;; p;ex;Ip;;s;Un; t;y;;r z;;leDy;; s;v;* p;ex;I]n;; ty;;c; m;;[;s;;cy;; x;rIr;t; p;rt; G;;t;Dy;; t;r ty;; b;;her f:ek:Dy;; j;;[;;r; n;;hIt;. ty;; m;;[;s;;n;; Immune suppressant a;E{;Q;;c;e G;;t;k: p;ir[;;m; B;;eg;;y;l; l;g;[;;r n;;hIt;. y;; p;àt;Il; Therapeutic cloning mh[;t;;t;.
p;[; Hy;; ES p;ex;I]cy;; s;]x;;eQ;n;;l; K;Up; Q;;im;*k: v; n;Eit;k: iv;re;Q; s;hn; k:r;y;l; l;g;t;;e a;he. j;e re;m;n; k:\q;ilk: v; Evangelical iK;xc;n; l;ek: , j;Iv;;c;I s;ur:v;;t; sF;Ib;;Ij; v; p;ur:{;b;Ij;;cy;; s;]m;Iln;;p;;s;Un; h;et;e as; m;;n;t;;t; , he l;ek: iv;x;e{; k:r:n; iv;r;eQ;;t; a;het;. k:;r[; p;ex;It;l; ny;Uikly;s; k:;$[;e mh[;j;e j;Iv;;c;I n;;s;;#I k:r[;e. p;[; Wd;rm;t;v;;dI v; x;;sF;Iy; iv;c;;rs;r[;I as;lele l;ek: ES cells m;Q;e j;Iv; as;t;;e as;] m;;n;t; n;;hIt;. ty;;]cy;; m;t;e m;Iln;;n;]t;r 14 vy;; idv;x;I j;Iv;;c;I s;ur:v;;t; h;et;e. ty;;]cy;; m;t;e ES cells Hy;; x;rIr;cy;; k:s;Dy;;hI B;;g;;cy;; p;ex;Ic; n;s;Un; ty;; x;rIr;m;Q;e n;vhe t;r p;>y;;eg;x;;Let; p;e!MI i#x;m;Q;e b;n;v;leDy;; a;het; . am;erik:et;Il b;hus;]Ky; 83 !kk:e l;ek: ES cells m;uLe an;ek: as;;Qy; re;g; b;re h;eW:n; m;;n;v;I j;Iv;n; s;uQ;;r[y;;cy;; a;x;em;uLe Hy;; s;]x;;eQ;n;;l; p;;i@]b;; det;;t;.
2001 cy;; a;\g;s! m;ihny;;t; p;>eis;#e]! b;ux;n;I ES cells f:T;: 60 p;ex;I]cy;;c; s;]x;;eQ;n;;l; s;rk:;rI an;ud;n; m;;ny; k:el]. g;B;;*t;Il ny;Uikly;s; k:;$Un; G;e[y;;cy;; k:s;Dy;;hI n;v;In; k:;m;;l; s;rk:;rI p;;i@]b;; n;;hI. ty;; 60 p;ex;I]p;Ek:I a;t;; f:T;: 22 Wp;y;;eg;;t; a;het;. b;;k:Icy;; k:s;l;t;rI s;]s;g;* h;eW:n; in;r:p;y;;eg;I z;;Dy;; a;het;. Hy;;m;uLe s;]x;;eQ;n;;v;r b;}Q;n;] a;lI a;het;. ty;;m;uLe K;Up;s;e am;erik:n; s;]x;;eQ;k: dus;Ry;; b;;y;;e!ekn;;|l;|ij;k:l k:]p;ny;;]k:#Un; m;dt;Ic;I ap;eZ;; k:rt; a;het; v;; ij;q;e Hy;; s;]x;;eQ;n;;l; k:;hI b;]Q;n;] n;;hIt; ax;; aeK;;ê; dus;Ry;; dex;;l; sq;l;]t;r k:r[y;;cy;; iv;c;;r;t; a;het;. K;Up;x;; b;;y;;e!kn;;|l;|ij;k:l k:]p;ny;; ES cells s;]x;;eQ;n;;c;; B;;v;I Wp;y;;eg; ids;t; as;Dy;;m;uLe ty;;v;r K;Up; K;c;* k:rt; a;het; . j;rI hI Wts;;h;c;I b;;b; a;he, t;rI Hy;; k:]p;ny;;]c;; m;uKy; het;U h; p;Es;; k:m;;v;[;] h; a;he ty;;m;uLe Hy;; s;]x;;eQ;n;;;t; K;Up; %up;ep;[;; a;he. Wl! s;rk:;rI an;ud;n;;n;e c;;lleDy;; s;]x;;eQ;n;;c;I x;;sF;N WG;#p;[;e v;;cy;t;; v; c;c;;* k:r: x;k:t;;t;. Hy;;m;uLe s;]x;;eQ;n;;c;I p;un;r:iT;: k:m;I h;et;e.j;rI k:e]d> s;rk:;r;n;e b;]Q;n;] G;;t;lI t;rI b;rIc;x;I r;jy;e ES cells c;; p;ursk:;r k:rt; a;het;. k:|ilf:;ein;*y;;t; n;;evhe]b;r 2004 s;;lI p;>;\p;;eiz;x;n; 71 n;;v;;c;; aek: @r;v; p;;s; z;;l; jy;;y;;eg;e 70 !kk:e j;n;t;en;e y;; s;]x;eQ;n;;l; p;;i@]b;; idl; a;he. Hy;; r;jy;;n;e 3 ib;lIy;n; #;|lr k:\ilf:;ein;*y;; win!!YU! a;|f: irj;n;rei!vh m;ei#is;n; Hy;; s;sq;el; ES cells v;r s;]x;;eQ;n; k:r[y;;s;;@I m;uF;:r k:ele. Hy;;p;;@e;p;;@ ny;Uj;s;I*s;;rKy;; wt;r r;jy;;t;hI Rutgers y;uni;vhis;*!I v; UMDNJ Hy;; d;enhI s;sq;;n;I im;LUn; ny;Uj;s;I* wins!!YU! a;f: s!em; se;l irs;c;* s;ur: k:el] a;he. dh; k:;e!I #;|ls;*cy;; K;;j;g;I v; in;m;K;;j;g;I s!em; s;el f:]#;t;le s;;#es;h; k:;e!I #;|ls;* he ny;Uj;s;I* r;jy; de[;;r a;he. Hy;;vy;it;irT;: 50 k:;e!I #;|ls;*c;I K;;j;g;I v; in;m;K;;j;g;I rkk:m; p;u$cy;; p;;c; v;{;;*]t; v;;p;rlI j;;[;;r a;he. ny;Uy;;\k:*, k:n;ei!k:!, iv;sk:;|ins;n; a;i[; wt;rhI im;#v;es!n;* r;jy;e y;;s;;rK;; Wp;k>:m; h;t;I G;et; a;het;. m;|s;|cy;us;e! r;jy;;t;Il h;v;*#* y;uin;vhis;*!In;e t;r hDlIc; aek:; h;v;*#* s!em; s;el irs;c;* wins;!y;U! Hy;; n;v;In; s;]sq;ec;] n;;m;k:r[; k:el]. ax;; s;rk:;rI k:uc;]b;[;em;uLe K;Up;s;e t;r:[; a;i[; hux;;r x;;sF;N s;rk:;rI an;ud;n;;v;r j;g;[;;Ry;; s;]sq;; s;;e#Un; j;;t; a;het;.
a;ix;y;;w* dex;;t;hI ES cell irs;c;* j;;er;t; c;;lU a;he. d. k:;eiry;;, j;p;;n;,is;]g;;p;Ur, t;Ev;;n; v; c;In; s;;rK;e dex; y;; Z;eF;;t; ag;>[;I b;n;le a;het;.m;;n;v;I g;B;;*c;] kl;ein;]g; k:r:n; ty;;n;I s!em; s;eDs;cy;; 11 p;>iF;:y;; s;ur: k:eDy;;, jy;; d;en; t;e 56 v;y;;cy;; 11 t;Dy;; 9 p;ex;]!;]cy;; j;n;uk:;x;I (Genes) hub;ehub; im;Lt; h;ety;;. Hy;;t; 8 r:g[; m;jj;;rjj;Ucy;; duK;;p;t;Ic;e h;et;e, aek: m;Q;um;eh as;lel; 6 v;{;;*c;; m;ulg;; h;et;; v; aek: 2 v;{;;*c;; Congental hypogammaglobulinemia s;;rKy;; duim;*L r;eg;;c;; ix;k:;r h;et;;. p;ihDy;;]d; p;;iScm;;ty; s;]x;;eQ;k: he s;]x;;eQ;n;;l; p;;i@]b;; ê;y;l; k:c;rt; h;et;e. p;[; h;v;*#* m;ei#k:l sk:Ul m;Q;Il s;]x;;eQ;k: a;i[; j;;g;it;k: s!em; se;l irs;c;* s;]sq;ec;; aQYZ; j;g;p;>is;à x;;sF;N #\;. len;;#* z;;\n; hY;]n;I ty;; k:;m;;c;; 'f:;rc; m;;e@; p;Dl; g;;@lel k:;m;' as;; g;;Erv; k:l;. ty;; dex;;t;lI s;ub;T;; v; s;rk:;rc;; p;;i@]b;; t;s;]c; K;;j;g;I s;]sq;;]n;I idlel] an;ud;n; y;;m;uLe K;Up;x;; a;ix;y;;w* dex;;t; he s;]x;;eQ;n; j;;er;t; c;;llel] a;he. t;s;]c; Hy;; dex;;t;Il K;Up;x;; f:!I*lI!Iv;r irs;c;* k:r[;;Ry;; s;]sq;;hI !;k:Un; idlel; g;B;* s;]x;;eQ;n;;s;;@I v;;p;r;y;c;I p;rv;;n;g;I det;;t;. B;;rt;hI s;rk:;rcy;;, K;;j;g;I s;]sq;;]cy;; v; IVF ikln;Iks;cy;; p;;i@]by;;m;uLe Hy;; s;]x;;eQ;n;;t; ag;>es;r a;he. B;;rt;;t; ES cell l;wns;c;; s;v;;e*tk:&{! K;ij;n;; a;he. Q;Ir:B;;w* a]b;;n;I]n;I s;ur: k:eleDy;; irl;y;ns; w#s!MIj;n;e m;u]b;w*t; Hy;; s;]x;;eQ;n;;s;;@I aek: s;]sq;; k:;$lI a;he. Hy;;t; B;rp;Ur p;Es;; as;Dy;;ix;v;;y; a]b;;n;Is;;rK;e m;;t;bb;r l;ek: y;; s;]x;;eQ;n;;t; p;#[;;r n;;hIt;. K;Up;x;; l;ek:;]cy;; m;t;e ES cells irs;c;* mh[;j;e s;;en;] de[;;rI k:;e]b;#I a;he.
j;rI hY;c;e K;Up; f:;y;de as;le t;rI Hy;;t; a#c;[;IhI K;Up; a;het;. 1)x;;sF;N;]n;; ES cells c;] v;eg;v;eg;Ly;; av;y;v;;]cy;; p;ex;I]t; r:p;;]t;r k:s;] k:r;y;c;] he aj;Un; n;I!s;] m;;iht; n;;hI, 2) Hy;; p;ex;Ic;] k:\ns;rcy;; p;ex;I]m;Q;e t;r r:p;;]t;r h;e[;;r n;;hI n;; Hy;;c;I k:;Lj;I ty;;]n;; v;;!t;e, 3) n;v;In; t;y;;r z;;leDy;; p;ex;I a;j;;r;c;; n;;x; ik:t;p;t; k:rt;Il Hy;;b;ddl t;e j;r; s;;x;]k: a;het;. p;r]t;u j;g;B;r c;;lleDy;; s;]x;;eQ;n;;m;uLe Hy;; p;>Sn;;]c;I WT;r] j;r:r im;Lt;Il Hy;;c;I ty;;]n;; K;;F;I a;he.

2005 s;;lcy;; m;e m;ihny;;t; s!em; sel ib;l h;W:s; a|f: rep;>ez;e]!ei!vh s;m;;er m;;]#[y;;t; a;l]]. p;e>is;#e]! b;ux;n;e he ib;l fe:!;LUn; l;iv;n; ax;I Q;m;k:I idlI. s;en;e! m;ej;;|ir!I lI#r irp;iblk:n; s;dsy; ib;l if>:s! Hy;;]n;Ie p;e>is;#e]! b;ux;cy;; iv;r;eQ;;t; j;;W:n; Hy;; ib;l;l; s;]m;t;I dx;*v;lI a;i[; s;g;^y;;]n;; a;Sc;y;;*c;; Q:kk:; idl;. Utah r;jy;;t;Il ab;;|x;*n; iv;r;eQ;I dus;r; irp;iblk:n; s;dsy; s;en;e!r a;\irn; h|c; y;;n;e iv;Q;;n; k:ele, "There is no greater way to promote life than to defeat death and stem cell research amy provide a way to do that. An embryo in a laboratory dish can be used for stem cell research because it has no capacity to develop into a person. Only after an embryo is transferred into a woman’s womb is that natural capacity to beaomce a person is attained and only then the government gains an intrest in protecting that entity." Provided the research is restricted to such cells and federally supervised, is this not a sensible and moral way to accelerate the time when the fruirs of this research can relieve human suffering. President Bush may try to stop ES stem cell research on religious and ethical grounds but he has to understand what Time magazine described succinctly "Science moves only in forward direction.”

Hy;; leK;;t;Il b;hut;ek: m;;iht;I NIH b;eq;es#;, m;eirl]# m;Q;Il K;Up;x;; leK;;]t;Un; G;et;lI g;elI a;he.
ih]dU Q;m;;*p;>m;;[;e j;Iv;;c;I s;ur:v;;t; hI b;Ij;;cy;; m;Iln;;p;;s;Un;c; h;et;e. p;[; ih]dU Q;m;* h; ait;x;y; s;hn;x;Il v; p;ur;eg;;m;I as;Dy;;m;uLe b;hut;ek: ih]dU l;ek:;]c;; s!em; se;l irs;c;*l; p;;i@]b;;c; r;ihl k:;r[; Hy;;p;;s;Un; b;Ry;;c; l;ek:;]cy;; b;Ry;;c; r;eg;;]c;] in;r;k:r[; h;e[;;r a;he.

-- y;x;v;]t; k:;rK;;n;Is;